6月24日（月）15時30分より，南7号館7階セミナー室において講演会を開催します。

開催日：2019年6月24日（月）
時刻：15:30-17:00
場所：南7号館7階セミナー室
講師：Professor Scott  J. Miller (Yale University, New Haven, CT, USA)
題目：Searching for Selective Catalytic Reactions in Complex Molecular Scaffolds
講演要旨： This lecture will describe recent developments in our efforts to develop low-molecular weight catalysts for asymmetric reactions.  Over time, our view of asymmetry has ebbed and flowed, with foci on enantioselectivity, site-selectivity and chemoselectivity.  In most of our current work, we are studying issues of enantioselectivity as a prelude to extrapolation of catalysis concepts to more complex stereochemical settings where multiple issues are presented in a singular substrate.  Some of the most dramatic illustrations will include “late stage functionalizations” of complex natural products.  Moreover, we continuously examine an interplay between screening of catalyst libraries and more hypothesis-driven experiments that emerge from screening results.  Some of the mechanistic paradigms, and their associated ambiguities, will figure strongly in the lecture.  Because most of our catalysts are peptide-based, analogies to enzymatic catalysts will also be presented.

Miller教授は，ペプチド触媒を有機分子触媒として用いた不斉合成反応の開発から全合成まで，幅広い有機合成化学分野の研究で優れた業績を上げています。
今回日本学術振興会の招へい研究者として来日されます。

ORCID : https://orcid.org/0000-0001-7817-1318

Miller教授のホームページです。
https://millerlab.yale.edu

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